Codein

1. What are codein and what are they used for?

Codeine-drop CT is a drug for the symptomatic treatment of irritating cough.
Codein are applied
- for the symptomatic treatment of irritating cough (unproductive cough).


2. What do you need to know before taking codein?


Codein should not be taken
- if you are hypersensitive to codeine, sodium disu...

1. What are codein and what are they used for?

Codeine-drop CT is a drug for the symptomatic treatment of irritating cough.
Codein are applied
- for the symptomatic treatment of irritating cough (unproductive cough).


2. What do you need to know before taking codein?


Codein should not be taken
- if you are hypersensitive to codeine, sodium disulfite or any of the other ingredients
of Codein are
- if you have functional respiratory (respiratory insufficiency) or respiratory (respiratory
depression)
- if you have an acute asthma attack
- if you have a chronic cough, B. a warning sign for a beginning
Asthma may be bronchial. In particular, it is important to look out for children
- of children under 2 years
- if you are about to give birth
- if you have been diagnosed with a threatening premature birth
- if you are taking certain medicines for depression called MAO inhibitors, such as B.
Moclobemide (see also "Taking codein with other medicinal products
Delivery ")
Take special care with codein
- if you are dependent on opioids
- if you suffer from impaired consciousness
- if you experience disturbances of the respiratory center (eg in conditions associated with increased intracranial pressure).
go forth) and disorders of respiratory function
- if the gallbladder has been removed (condition after cholecystectomy)
- if your cough is accompanied or increased by increased mucus production
other sputum comes. In these cases, codein may only become more stringent
 
Take benefit-risk consideration by your doctor as it creates a dangerous secretion
can come
- if you are one of the persons suffering from a genetic variant of the liver
enzyme CYP2D6 (polymorphism) convert codeine very rapidly to morphine, since it is in
In this case, a relative overdose can occur.
at higher doses:
- if you suffer from low blood pressure due to lack of fluids
children
This medicine should not be given to children under 2 years of age.
Taking codein with other medicines
Tell your doctor or pharmacist if you are taking / using any other medicines.
or recently used, even if it is not a prescription
medicinal products subject to the duty to pay.
The following drugs may be influenced in their effect by codein, or
in turn, affect the effect of codein. Therefore ask for a similar
In the case of early administration of the following drugs with codeine-drop CT, be sure to consult your doctor.
- sedative and sleep aid
- psychotropic drugs (phenothiazines such as chlorpromazine, thioridazine, perphenazine)
- Agents for the treatment of allergies (antihistamines such as promethazine, meclozin)
- hypotensive agents (antihypertensive agents).
- tricyclic antidepressants such. Imipramine, amitriptyline and opipramol
- certain strong painkillers such. B. buprenorphine, pentacozin (so-called
 
partial opioid agonists / antagonists)
- cimetidine
MAO inhibitors such. B. Moclobemide:
Codein may not be used until two weeks after the end of MAO inhibitor therapy
 
be taken.
Taking codein together with food and drink
Do not drink alcohol while using codein. Codeintropfen-
CT, together with alcohol, diminishes the ability to solve complex tasks and tasks
 
Concentration (psychomotor performance) stronger than the individual substances.
pregnancy and breast feeding period
If you are pregnant, you may only codein on your express order
Doctors take as unwanted effects on the development of the unborn child
can not be excluded.
Do not use codein when you are approaching delivery or imminent premature birth,
because the codeine contained in drug code-codeine happens to pass the placental barrier and the
Newborn can lead to respiratory problems.
For longer term use of codein, a code dependency of the
 
develop unborn child. Reports of withdrawal symptoms in the newborn after
repeated use of codeine in the last third of pregnancy are present.
Therefore, contact your doctor immediately if you are planning to become pregnant or
are already pregnant to discuss the continuation or conversion of therapy
to advise.
lactation
Codeine and its degradation product morphine are excreted in breast milk.
In general, single use of codein can be performed by your doctor
recommended dose to be breastfed. If your child has drinking difficulties or unusual
calm.

3. How to take codein?

At the beginning of treatment, look for any signs of overdose (see "If
You have taken a greater amount of codein than you should "). by virtue of
a genetic variant of the liver isoenzyme CYP2D6 (polymorphism) becomes codeine
  Some people convert very quickly to morphine, leading to a relative overdose
can lead.
Always take codein exactly as your doctor has told you. Please ask
Check with your doctor or pharmacist if you are not sure

4. What side effects are possible?

Like all medicines, codein can have side effects, although not everybody does
must occur.
The evaluation of side effects is based on the following frequencies:
very often
more than 1 in 10 people treated
frequently
less than 1 in 10, but more than 1 in 100 people
occasionally
less than 1 in 100, but more than 1 in 1000 people
Rare
less than 1 in 1000, but more than 1 in 10,000 people
very rare
less than 1 in 10,000 people, including isolated cases
nervous system
frequently:
 
mild headache, mild drowsiness
occasionally:
sleep disorders
gastrointestinal tract
very common: nausea, u. U. until vomiting (especially at the beginning of therapy), constipation
(Constipation)
occasionally:
dry mouth
respiratory tract
occasionally:
shortness of breath skin
occasionally:
Itching (pruritus), hives (urticarial exanthema)
Rare:
severe allergic reactions including Stevens-Johnson syndrome
At higher doses or in particularly sensitive patients dose-dependently
 
Ability to optically fix objects (visuomotor coordination) and impair vision. Also disturbances of the respiratory drive (respiratory depression)
and morbid high spirits (euphoria) occur.
Codeine may, especially in single doses above 60 mg,
tonus) of the involuntary muscles (smooth muscle) z. B. intestinal muscles, increase bladder muscles.
With high therapeutic doses and with poisonings fainting (syncope) and
Hypotension may occur in patients with pre-existing pulmonary dysfunction
the occurrence of pulmonary edema can be expected.
Other possible side effects
Sodium disulfite rarely causes hypersensitivity reactions and bronchospasm (bronchospasm).
Tell your doctor or pharmacist if any of the side effects you listed
or you notice any side effects not listed in this leaflet.

5. How to keep codein?

Store drug out of reach of children.
Do not store above 25 ° C.
This medicine is stable for 6 months after onset.
You may take the medicinal product according to the expiry date stated on the packaging and on the label.
Do not use the date.
The medicinal product must not be disposed of in waste water or household waste. Ask your
Pharmacist how to dispose of the medicine when you no longer need it. These measures
helps to protect the environment.

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